Interleukin 33: A new target against gastrointestinal cancer?
نویسندگان
چکیده
منابع مشابه
Interleukin (IL)-33: new therapeutic target for atopic diseases.
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is produced when epithelial and endothelial cells are exposed to stimuli. Hematopoietic cells such as macrophages also produce IL-33. IL-33 is considered to function as an 'alarmin', activating various immune cells through its receptor ST2, which leads to the production of various molecules. The IL-33-induced production of pro-infla...
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JSS has received financial compensation from and served on advisory boards for Roche and is an investigator in clinical trials of tocilizumab. RNM has received consulting fees from Chugai; served on an ad hoc advisory board for Roche; and was responsible for the planning and preparation for publication of the Phase II European (CHARISMA) trial of tocilizumab with and without methotrexate. A pat...
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ژورنال
عنوان ژورنال: European Journal of Cancer
سال: 2020
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(20)31239-9